Coeliac disease, also spelled celiac disease, is a long term autoimmune disorder primarily affecting the small intestine that occurs in people who are genetically. World Gastroenterology Organisation Global Guidelines. Celiac disease. Review Team. Bai (Chair, Argentina), Carolina Ciacci (Co-chair, Italy. Celiac disease, caused by allergy to gluten present in wheat and related grains, is a disorder of considerable and increasing importance in Western countries1. ![]() Celiac Disease (Sprue): Practice Essentials, Background, Pathophysiology. Ludvigsson JF, Zingone F, Tomson T, Ekbom A, Ciacci C. Increased risk of epilepsy in biopsy- verified celiac disease: A population- based cohort study. Rubio- Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA, American College of Gastroenterology. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol. ACG issues celiac disease guidelines. ![]() May 3, 2. 01. 3. Available at http: //www. Accessed: May 1. 5, 2. Green PH, Cellier C. Celiac disease. N Engl J Med. Oct 2. 5. 3. 57(1. ![]() Back to Top. Pathophysiology. Celiac disease is a multifactorial and a multisystem disorder involving a genetic predisposition, environmental exposure of the small. ![]() Key Clinical Points Celiac Disease. Once considered a gastrointestinal disorder that mainly affects white children, celiac disease is now known to affect persons of. BACKGROUND AND OBJECTIVE: Previous research suggests an association of celiac disease (CD) with anorexia nervosa (AN), but data are mostly limited to case reports. Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest. 1. Green PH, Lebwohl B, Greywoode R. Celiac disease. J Allergy Clin Immunol. Kelly CP, Bai JC, Liu E, Leffler DA. Advances in diagnosis and management of celiac disease. Gastroenterology. Tursi A, Brandimarte G, Giorgetti GM. Prevalence of antitissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease. 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Cancer incidence in a population- based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology. Catassi C, Ratsch IM, Fabiani E, et al. Coeliac disease in the year 2. Jan 2. 2. 3. 43(8. Collin P, Kaukinen K, Vogelsang H, et al. Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy- proven European multicentre study. Eur J Gastroenterol Hepatol. Cristofori F, Fontana C, Magista A, et al. Increased prevalence of celiac disease among pediatric patients with irritable bowel syndrome: a 6- year prospective cohort study. JAMA Pediatr. 1. 68(6): 5. Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Farrell RJ, Kelly CP. Celiac sprue. N Engl J Med. Jan 1. 7. 3. 46(3): 1. Fasano A, Berti I, Gerarduzzi T, et al. Prevalence of celiac disease in at- risk and not- at- risk groups in the United States: a large multicenter study. Arch Intern Med. 2. Feb 1. 0. 1. 63(3): 2. Ferguson A, Arranz E, O'Mahony S. Clinical and pathological spectrum of coeliac disease- -active, silent, latent, potential. Celiac disease screening should focus on kids with IBS. Available at http: //www. April 2. 1, 2. 01. Accessed: April 2. Godkin A, Jewell D. The pathogenesis of celiac disease. Gastroenterology. Greco L, Romino R, Coto I, et al. The first large population based twin study of coeliac disease. Green PH, Jabri B. Coeliac disease. 3. Endoscopy without biopsy may miss many with celiac disease. Reuters Health Information. March 1. 7, 2. 01. Coeliac disease: the cause of the various associated disorders? Eur J Gastroenterol Hepatol. Johnson TC, Diamond B, Memeo L, et al. Relationship of HLA- DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol. 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Coeliac disease in Middle Eastern countries: a challenge for the evolutionary history of this complex disorder? Dig Liver Dis. 3. Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. Salmi TT, Collin P, Korponay- Szabo IR, et al. Endomysial antibody- negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Sanders DS, Hurlstone DP, Mc. Alindon ME, et al. Antibody negative coeliac disease presenting in elderly people- -an easily missed diagnosis. Sategna- Guidetti C, Pulitano R, Grosso S, et al. Serum Ig. A antiendomysium antibody titers as a marker of intestinal involvement and diet compliance in adult celiac sprue. J Clin Gastroenterol. Smedby KE, Akerman M, Hildebrand H, et al. Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy- type T cell lymphoma. 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